Definition of diabetes and its classification

Diabetes mellitus is a group of metabolic (metabolic) diseases characterized by hyperglycemia, which is the result of defects in insulin secretion, the effects of insulin, or both of these factors.

WHO 1999

Classification of diabetes mellitus (WHO, 1999)

Type 1 diabetes• Autoimmune • IdiopathicPancreatic β-cell destruction, usually resulting in absolute insulin deficiency
Type 2 diabetesWith predominant insulin resistance and relative insulin insufficient NOSTA or with primary defect in insulin resistance in insulin secretion with or without          
Other types of diabetes *• Genetic defects in the function of? -Cells • Genetic defects in the action of insulin • Diseases of the exocrine pancreas • Endocrinopathies • Diabetes induced by drugs or chemicals • Infections • Unusual forms of immune-mediated diabetes • Other genetic syndromes associated with diabetes mellitus
Gestational diabetesOccurs during pregnancy

* Other types of diabetes

Genetic defects in the function of? -CellsMODY-1MODY-2MODY-3MODY-4Mitochondrial DNA mutationOther
Genetic defects in the action of insulinType A Insulin ResistanceLeprechaunismRabson-Mendenhall Syndrome Lipoatrophic DiabetesOther
Diseases of the exocrine pancreasPancreatitisTrauma / PancreatectomyNeoplasiaCystic fibrosisHemochromatosisFibrocalcule pancreatopathy
Drug or Chemical DiabetesVacorThiazidesPentamidine Dilantin Nicotinic acid ? -Interferon Glucocorticoids ? -Adrenoblockers Thyroid hormones Diazoxide Others                                            
InfectionsCongenital rubellaCytomegalovirusOther

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