Diabetes mellitus is a group of metabolic (metabolic) diseases characterized by hyperglycemia, which is the result of defects in insulin secretion, the effects of insulin, or both of these factors.
WHO 1999
Classification of diabetes mellitus (WHO, 1999)
| Type 1 diabetes• Autoimmune • Idiopathic | Pancreatic β-cell destruction, usually resulting in absolute insulin deficiency |
| Type 2 diabetes | With predominant insulin resistance and relative insulin insufficient NOSTA or with primary defect in insulin resistance in insulin secretion with or without |
| Other types of diabetes * | • Genetic defects in the function of? -Cells • Genetic defects in the action of insulin • Diseases of the exocrine pancreas • Endocrinopathies • Diabetes induced by drugs or chemicals • Infections • Unusual forms of immune-mediated diabetes • Other genetic syndromes associated with diabetes mellitus |
| Gestational diabetes | Occurs during pregnancy |
* Other types of diabetes
| Genetic defects in the function of? -Cells | MODY-1MODY-2MODY-3MODY-4Mitochondrial DNA mutationOther |
| Genetic defects in the action of insulin | Type A Insulin ResistanceLeprechaunismRabson-Mendenhall Syndrome Lipoatrophic DiabetesOther |
| Diseases of the exocrine pancreas | PancreatitisTrauma / PancreatectomyNeoplasiaCystic fibrosisHemochromatosisFibrocalcule pancreatopathy |
| Endocrinopathies | AcromegalySyndromeCushingGlucagonPheochromocytomaThyrotoxicosisSomatostatinAldosteromaOther |
| Drug or Chemical Diabetes | VacorThiazidesPentamidine Dilantin Nicotinic acid ? -Interferon Glucocorticoids ? -Adrenoblockers Thyroid hormones Diazoxide Others |
| Infections | Congenital rubellaCytomegalovirusOther |