Endocrine disorders with ataxia of Friedreich. Causes of diabetes

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Approximately 40% of patients with Friedreich’s ataxia have impaired glucose tolerance; diabetes is observed in 10-20% of patients (Harding A.E., Hebinck J. et al.). Diabetes mellitus with Friedreich ataxia is mitochondrial in nature and is caused by pancreatic dysfunction and impaired insulin secretion (Fantus I. et al.). Moreover, in patients, as a rule, there are….

Diabetes as a cause of heart disease

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In patients with diabetes mellitus (DM), compared with patients without diabetes, there is an increased prevalence of atherosclerosis and coronary heart disease (CHD), as well as higher rates of morbidity and mortality after acute coronary syndrome and myocardial infarction. An analysis of the data collected in the OASIS registry during an average of 2 years….

Diseases of the parathyroid gland on an ECG. Diabetes mellitus and pneumothorax on an ECG

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Almost all ECG changes detected in such processes occur as a result of changes in the concentration of extracellular calcium in the form of hypercalcemia or hypocalcemia. With hypoparathyroidism, the only obvious change is the lengthening of the QTc interval, which occurs due to the ST segment, since the duration of the T wave is….

Diabetes is a disaster in modern society

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Diabetes mellitus is spreading rapidly around the planet. The main reason scientists and doctors call a significant change in lifestyle, the nature of nutrition. The planet’s population has begun to move less and eat more. The leaders in the number of patients are India, USA, China, Russia.Diabetes mellitus is a disease that occurs due to a lack of….

Patology of the fetus in case of diabetes in the mother. Features

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In women with insulin-dependent diabetes mellitus, it is much more difficult to maintain and control the disease during pregnancy. In addition, the need for insulin increases. Poorly controlled diabetes in women leads to the development of polyamnion and preeclampsia, an increase in the frequency of early miscarriages, congenital malformations and late unexplained intrauterine death.   Ketoacidosis leads to high fetal mortality. With meticulous….

Genetics of type I diabetes. Inheritance Features

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There are two main types of diabetes: type I (insulin-dependent – IDDM) and type II (non-insulin-dependent – IDDM), which make up 10 and 88% of all cases, respectively. They differ in typical age of onset, concordance of identical twins and association with specific alleles of the main histocompatibility complex (MHC – major histocompatibility complex). Family accumulation is observed in….

Diabetes. Reasons and development mechanisms

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In 1994, 110.4 million patients with diabetes were registered in the world, by 2000 their number had almost doubled, amounting to about 175 million, by 2025 there would be about 300 million patients with diabetes in the world (Fujimoto WY). The socio-economic significance of the problem is difficult to overestimate. Currently, about 200 million patients with diabetes….

Diabetes Classification

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According to the WHO classification , the main forms of diabetes were recognized as insulin-dependent (insulin-deficient) diabetes mellitus (IDDM), or type I diabetes mellitus, and non-insulin-dependent diabetes mellitus (NIDDM), or type II diabetes mellitus. Next, a new type of diabetes associated with malnutrition (ADHD), as well as other types of diabetes associated with various secondary diseases, would be highlighted.   According….